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Summary of genome sequences and mutations in human coronaviruses. (A) Numbe... Open Access
Published: 26 November 2025
Figure 2.
Summary of genome sequences and mutations in human coronaviruses. (A) Number of genome sequences available for seven human coronaviruses. (B) Summary of mutation counts in the SARS-CoV-2 genome.
Journal Article
HCoVDB: a comprehensive database encompassing viral genomes, drug targets, and therapeutics of human coronaviruses Open Access
Database, Volume 2025, 2025, baaf079, https://doi.org/10.1093/database/baaf079
Published: 26 November 2025
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The framework of the HCoVDB database. This database comprises three core co... Open Access
Published: 26 November 2025
Figure 1.
The framework of the HCoVDB database. This database comprises three core components: (1) genomic-level annotations, (2) target protein–compound interactions, and (3) antiviral activity data of small molecules.
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Screenshot illustrating an example of genome exploration in the HCoVDB data... Open Access
Published: 26 November 2025
Figure 3.
Screenshot illustrating an example of genome exploration in the HCoVDB database. (A) A detailed list of sources and basic information on genomic sequences from human coronaviruses. (B) An evolutionary tree constructed from representative genomic sequences. (C) A functional annotation of viral mutati
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Screenshot illustrating an example of target exploration in the HCoVDB data... Open Access
Published: 26 November 2025
Figure 4.
Screenshot illustrating an example of target exploration in the HCoVDB database. (A) Basic information on the SARS-CoV-2 protein NSP1. (B) Options to view detailed molecular docking results by selecting the drug ‘Montelukast’.
Journal Article
CircAI: a comprehensive database of CircRNA associated with A-to-I RNA editing Open Access
Database, Volume 2025, 2025, baaf075, https://doi.org/10.1093/database/baaf075
Published: 22 November 2025
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An overview of the ecosystem is provided. Panel (a) shows the extract-trans... Open Access
Published: 22 November 2025
Figure 4.
An overview of the ecosystem is provided. Panel (a) shows the extract-transform-load (ETL) process. Panel (b) Shows examples of tools provided (top) and tools that could easily be used. Panel (c) Notes how these user communities can create reproducible outputs.
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Global characteristics of RNA editing. (A) Number of samples for each speci... Open Access
Published: 22 November 2025
Figure 2.
Global characteristics of RNA editing. (A) Number of samples for each species. (B) Number of editing sites identified in each species. (C) Number of 12 editing types per species. (D) Distribution of RNA editing sites in different genomic regions. (E) Functional annotations of RNA editing sites for e
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Characterization of different species of circRNAs. (A) Number of circRNAs i... Open Access
Published: 22 November 2025
Figure 3.
Characterization of different species of circRNAs. (A) Number of circRNAs in different species. (B) Full-length sequences of circRNAs for each species. (C) The junction ratio of circRNAs for each species. (D) Percentage of circRNA types.
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Comprehensive view of CircAI database. Open Access
Published: 22 November 2025
Figure 5.
Comprehensive view of CircAI database.
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The page of CircAI’s (A) circRNA and (B) RNA editing detailed information. Open Access
Published: 22 November 2025
Figure 6.
The page of CircAI’s (A) circRNA and (B) RNA editing detailed information.
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An example of the documentation for a single variable. The values associate... Open Access
Published: 22 November 2025
Figure 1.
An example of the documentation for a single variable. The values associated with ‘Variable Name’, ‘SAS Label’, and ‘Target’ are extracted and used as metadata. The Table describes the code used in the raw SAS data file; the ‘Value Description’ column gives the English description of what the code m
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Documentation for the SMQ020 and SMD030 variables. Depending on the answer ... Open Access
Published: 22 November 2025
Figure 2.
Documentation for the SMQ020 and SMD030 variables. Depending on the answer to SMQ020, the next question (SMD030) may or may not be asked. The answer to questions not asked will be recorded as ‘Missing’, which is potentially misleading. SMQ020–SMD030 flow
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. CircAI database functional analysis framework. (A) Statistics of multispe... Open Access
Published: 22 November 2025
Figure 4
. CircAI database functional analysis framework. (A) Statistics of multispecies circRNA editing events. (B) Regulatory impact of RNA editing on circRNA–miRNA interactions. (C) RNA editing-mediated alterations in circRNA coding potential. (D) Workflow for identifying circRNA edQTLs. (E) Structural co
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Architecture design of CircAI. Open Access
Published: 22 November 2025
Figure 7.
Architecture design of CircAI.
Journal Article
Enhancing statistical analysis of real world data Open Access
Database, Volume 2025, 2025, baaf073, https://doi.org/10.1093/database/baaf073
Published: 22 November 2025
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Average BMI for 40–59 year olds by Cycle for four population subgroups. The... Open Access
Published: 22 November 2025
Figure 3.
Average BMI for 40–59 year olds by Cycle for four population subgroups. The estimates and confidence intervals for average BMI within each subgroup is computed using the estMean function in the survey package, which takes into account the complex survey design of NHANES. Although the confidence inte
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Workflow for the construction of CircAI. Open Access
Published: 22 November 2025
Figure 1.
Workflow for the construction of CircAI.
Journal Article
PolED: a manually curated database of functional studies of POLE and POLD1 variants reported in humans Open Access
Database, Volume 2025, 2025, baaf076, https://doi.org/10.1093/database/baaf076
Published: 20 November 2025
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PolED architecture and interface. The PolED database is implemented as a Fa... Open Access
Published: 20 November 2025
Figure 3.
PolED architecture and interface. The PolED database is implemented as a FastAPI-based web application, deployed using Uvicorn, and managed via systemd. The backend stores variant data in an SQLite database and serves both static files and dynamic content. Users can interact with PolED through a web
